AUP-16 (AUP1602-C)

Delivers siRNA, antisense oligonucleotides, linear or circular mRNA and other RNA modalities to extrahepatic tissues - demonstrated across various indications in oncology (e.g. PDAC, breast cancer, ovarian cancer, lung cancer, melanoma, ATLL, TME), and inflammatory / autoimmune diseases (e.g. OA, RA, enterocolitis), CV (e.g. atherosclerosis, aortic aneurysm)

Crohn's disease

MV-010 is an orally available recombinant bacterial enzyme formulated by an exclusively licensed platform to restore intestinal immune system homeostasis in inflammatory bowel disease (IBD).