Fundamentals in downstream processing

This 3-day training course provides an introduction to downstream processing with hands-on practical and theory in the field.

The general aims of this course are to enable a non-expert in the field of downstream processing:

• To be able to understand what a bioprocess is
• To have the necessary theoretical and practical knowledge to understand what separation techniques to use at which stage of a process and for what purpose
• To understand and perform Tangential Flow Filtration (TFF), packing of a 20 cm diameter chromatography column and to run a preparative chromatgraphy purification with the AKTA chromatography from Cytivia
• To provide the basis for more advanced practical development to become an expert in the field (if desired)
• To enable people in USP to transfer to DSP

This training program includes theoretical and practical parts on Tangential Flow Filtration (TFF): Ultrafiltration and Diafiltration; as well as theoretical and practical parts on chromatography: Packing and characterization of a 20 cm diameter column, Hands on experience with preparative chromatography.