GABAB PAM - Substance Use Disorder

Indicaton

Milestone: IND enabling studies started in H2 2024

Our partner, Indivior has selected a GABAB PAM drug candidate from our research program for future development in substance use disorder and will now undertake all future development of their selected compound.

Under the terms of the agreement, Addex is eligible for payment of up to USD 330 million on successful achievement of prespecified regulatory, clinical and commercial milestones as well as tiered royalties on the level of net sales from high single digits up to low double-digit.

We believe that substance use disorder is an indication with a significant commercial opportunity. Existing therapies often do not provide effective control of symptoms or have side effects that discourage adherence. Subject to regulatory approval, we believe that GABAB PAM may offer an innovative and differentiated treatment approach from existing therapies and may provide benefit to patients.

This program is currently in IND enabling studies phase.

Therapeutic indications

Type of product

Small molecule

Table

Phase

Discovery
Partnering status

Partnered
Partner

Indivior PLC

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