The brain-penentrant mTOR-only inhibitor PQR626 is currently in preclinical validation stage.
Multiple indications in metastatic breast cancer, early breast cancer and metastatic gastric cancer
Multiple indications in Non-Hodgkin's lymphoma (NHL), Chronic lymphocytic leukaemia (CLL), Rheumatoid arthritis, Granulomatosis with polyangiitis and microscopic polyangiitis and Pemphigus vulgaris